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RNA m6sup>A modification and its function in diseases

Jiyu Tong, Richard A. Flavell, Hua-Bing Li

Frontiers of Medicine 2018, Volume 12, Issue 4, Pages 481-489 doi: 10.1007/s11684-018-0654-8

Abstract:

N6sup>-methyladenosine (m6sup>A) is the most common post-transcriptional RNAsup>A modification could be installed by m6sup>A “writers” composed of core catalyticThe function of m6sup>A is executed by m6sup>A “readers” that bind to m<supHowever, the mechanism and the regulatory network of m6sup>A are still largely unknown.Moreover, investigations of the m6sup>A physiological roles in human diseases are limited.

Keywords： RNA modification m6sup>A immunity cancer epigenetics

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High frequency of alternative splicing variants of the oncogene in neuroendocrine tumors of the pancreas and breast

Frontiers of Medicine Pages 907-923 doi: 10.1007/s11684-023-1009-7

Abstract: Box 7-containing FAK variants (FAK6/7sup>) were observed in 7 (87.56/7sup> was positive in 34 (75.6%) of 45 pancreatic NENs, 19 (47.5>6/7sup> was positive in 14 (93.3%) of 15 BrNECs but 0 in 23 non-NEC breast6/7sup> in cells.These results suggested that FAK6/7sup> could be a biomarker of NENs and represent

Keywords： FAK6/7sup> SRRM4 neuroendocrine neoplasms pancreas breast

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Study on Algorithm A*sup> Based on Dynamic Representation of Binary Tree for Environment and Robotic

Tang Ping,Yang Yimin

Strategic Study of CAE 2002, Volume 4, Issue 9, Pages 50-53

Abstract: A new algorithm A*sup> , which plans the path of soccer robots in complicated environments is

Keywords： dynamic binary-tree algorithm A*sup> path planning

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Clinical significance of CD34+sup>CD117dimsup>/CD34+sup>CD117brisup> myeloblast-associated

Xueping Li, Yuting Dai, Bing Chen, Jinyan Huang, Saijuan Chen, Lu Jiang

Frontiers of Medicine 2021, Volume 15, Issue 4, Pages 608-620 doi: 10.1007/s11684-021-0836-7

Abstract: t(8;21)(q22;q22) acute myeloid leukemia (AML) is a highly heterogeneous hematological malignancy with a high relapse rate in China. Two leukemic myeloblast populations (CD34 CD117 and CD34 CD117 ) were previously identified in t(8;21) AML, and CD34 CD117 cell proportion was determined as an independent factor for this disease outcome. Here, we examined the impact of CD34 CD117 /CD34 CD117 myeloblast-associated gene expression on t(8;21) AML clinical prognosis. In this study, 85 patients with t(8;21) AML were enrolled. The mRNA expression levels of CD34 CD117 -associated genes ( , , and ) and CD34 CD117 -associated genes ( , , and ) were measured using quantitative reverse transcription PCR. Associations between gene expression and clinical outcomes were determined using Cox regression models. Results showed that patients with high , , or expression had significantly inferior overall survival (OS), whereas those with high or expression showed relatively favorable prognosis. Univariate analysis revealed that CD19, CD34 CD117 proportion, mutation, minimal residual disease (MRD), and expression levels of , , , and were associated with OS. Multivariate analysis indicated that mutation, MRD and and expression levels were independent prognostic variables for OS. Identifying the clinical relevance of CD34 CD117 /CD34 CD117 myeloblast-associated gene expression may provide new clinically prognostic markers for t(8;21) AML.

Keywords： t(8 21)(q22 q22) AML CD34+sup>CD117dimsup>/ CD34+sup>CD117brisup> cell population

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K+sup> and Na+sup> fluxes in roots of two Chinese Iris populations

Pinfang LI,Biao ZHANG

Frontiers of Agricultural Science and Engineering 2014, Volume 1, Issue 2, Pages 144-149 doi: 10.15302/J-FASE-2014016

Abstract: Maintenance of ion homeostasis, particularly the regulation of K and Na uptake, is important for all plants to adapt to salinity. Observations on ionic response to salinity and net fluxes of K , Na in the root exhibited by plants during salt stress have highlighted the need for further investigation. The objectives of this study were to compare salt adaptation of two Chinese Iris ( Pall. var. (Fisch.) Koidz.) populations, and to improve understanding of adaptation to salinity exhibited by plants. Plants used in this study were grown from seeds collected in the Xinjiang Uygur Autonomous Region (Xj) and Beijing Municipality (Bj), China. Hydroponically-grown seedlings of the two populations were supplied with nutrient solutions containing 0.1 (control) and 140 mmol·L NaCl. After 12 days, plants were harvested for determination of relative growth rate and K , Na concentrations. Net fluxes of K , Na from the apex and along the root axis to 10.8 mm were measured using non-invasive micro-test technique. With 140 mmol·L NaCl treatment, shoots for population Xj had larger relative growth rate and higher K concentration than shoots for population Bj. However, the Na concentrations in both shoots and roots were lower for Xj than those for Bj. There was a lower net efflux of K found in population Xj than by Bj in the mature zone (approximately 2.4-10.8 mm from root tip). However, no difference in the efflux of Na between the populations was obtained. Population Xj of continued to grow normally under NaCl stress, and maintained a higher K /Na ratio in the shoots. These traits, which were associated with lower K leakage, help population Xj adapt to saline environments.

Keywords： Koidz population K+sup> and Na+sup> ion flux non-invasive micro-test technique

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Recent Advances in 19sup>Fluorine Magnetic Resonance Imaging with Perfluorocarbon Emulsions Review

Wickline,Gregory M. Lanza

Engineering 2015, Volume 1, Issue 4, Pages 475-489 doi: 10.15302/J-ENG-2015103

Abstract:
The research roots of 19sup>fluorine (19sup>F) magnetic resonance imaging (MRI) dateOver that time span, 1sup>H imaging flourished and was adopted worldwide with an endless arrayFor many years during this timeframe, 19sup>F imaging research continued at a slow pace as the>19sup>F imaging has exploded.In part, this is due to advances in MRI instrumentation, 19sup>F/1sup>H coil designs, and

Keywords： fluorine magnetic resonance imaging (MRI) dual-tuned coil perfluorocarbon angiogenesis cell labeling

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Removal of ammonium and nitrate through Anammox and FeS-driven autotrophic denitrification

Frontiers of Environmental Science & Engineering 2023, Volume 17, Issue 6, doi: 10.1007/s11783-023-1674-4

Abstract:
● Simultaneous NH₄+sup>/NO₃–sup

Keywords： Anammox Denitrification FeS NH₄+sup>/NO₃−sup> Sulfammox

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Selective recovery of Cu

Haiping LUO,Bangyu QIN,Guangli LIU,Renduo ZHANG,Yabo TANG,Yanping HOU

Frontiers of Environmental Science & Engineering 2015, Volume 9, Issue 3, Pages 522-527 doi: 10.1007/s11783-014-0633-5

Abstract: concentrations from 250 to 1000 mg·L , and maximum power densities increased from 3.1±0.5 to 5.4±0.6 W·mconcentrations from 250 to 1000 mg·L , and maximum power densities increased from 3.0±0.1 to 6.3±1.2 W·m

Keywords： bioelectrochemical system Cu2+sup> Ni2+sup> selective recovery

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Advances of 12thsup> CAPS research symposium: young chemists and chemical engineers fronts

Guoping Hu, Baiqian Dai

Frontiers of Chemical Science and Engineering 2021, Volume 15, Issue 3, Pages 461-463 doi: 10.1007/s11705-020-2026-6

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Effect of noble metal nanoparticle size on C–N bond cleavage performance in hydrodenitrogenation: a study of active sites

Frontiers of Chemical Science and Engineering 2023, Volume 17, Issue 12, Pages 1986-2000 doi: 10.1007/s11705-023-2337-5

Abstract: Results showed a 13 times higher reaction rate for sp3sup>-hybridized C–N bond cleavage than sp2sup>-hybridized C–N bond cleavage, while the reaction rate tended to increase first and then

Keywords： sp3sup>/sp2sup>-hybridized C–N bond noble metal nanoparticle catalytic active site turnover

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Symbiotic performance, shoot biomass and water-use efficiency of three groundnut (

Sofiya K. MUHABA, Felix D. DAKORA

Frontiers of Agricultural Science and Engineering 2020, Volume 7, Issue 4, Pages 455-466 doi: 10.15302/J-FASE-2020354

Abstract:
Phosphorus is a key nutrient element involved in energy transfer for cellular metabolism, respiration and photosynthesis and its supply at low levels can affect legume nodulation, N fixation, and C assimilation. A two-year field study was conducted in Ethiopia in 2012 and 2013 to evaluate the effects of P supply on growth, symbiotic N nutrition, grain yield and water-use efficiency of three groundnut genotypes. Supplying P to the genotypes significantly increased their shoot biomass, symbiotic performance, grain yield, and C accumulation. There was, however, no effect on shoot δ C values in either year. Compared to the zero-P control, supplying 40 kg·ha P markedly increased shoot biomass by 77% and 66% in 2012 and 2013, respectively. In both years, groundnut grain yields were much higher at 20 and 30 kg·ha P. Phosphorus supply markedly reduced shoot δ N values and increased the %Ndfa and amount of N-fixed, indicating the direct involvement of P in promoting N fixation in nodulated groundnut. The three genotypes differed significantly in δ N, %Ndfa, N-fixed, grain yield, C concentration, and δ C. The phosphorus × genotype interaction was also significant for shoot DM, N content, N-fixed and soil N uptake.

Keywords： shoot yield N-fixed %Ndfa δ15sup>N δ13sup>C water-use efficiency

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Effects of La, Ce on nitrogen removal in sequencing batch reactor

Qing XIA , Rui LIANG , Yuning HONG , Lili DING , Hongqiang REN , Yuxiang MAO , Mingyu ZHAO ,

Frontiers of Environmental Science & Engineering 2009, Volume 3, Issue 3, Pages 369-374 doi: 10.1007/s11783-009-0036-1

Abstract: Batch experiments were conducted to study the short-term biological effects of rare earth ions (La, Ce) and their mixture on the nitrogen removal in a sequencing batch reactor (SBR). The data showed that higher NH―N removal rate, total inorganic nitrogen removal efficiency, and denitrification efficiency were achieved at lower concentrations of rare earth elements (REEs) (<1mg/L). In the first hour of the aeration stage of SBR, the presence of REEs increased the total inorganic nitrogen removal efficiency and NH―N removal efficiency by 15.7% and 10%―15%, respectively. When the concentrations of REEs were higher than 1mg/L, the total inorganic nitrogen removal efficiency decreased, and nitrate was found to accumulate in the effluent. When the concentrations of REEs was up to 50.0mg/L, the total inorganic nitrogen removal efficiency was less than 30% of the control efficiency with a high level of nitrate. Lower concentrations of REEs were found to accelerate the nitrogen conversion and removal in SBR.

Keywords： rare earth La3+sup> Ce3+sup> inorganic nitrogen nitrogen removal sequencing batch reactor

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Innate and adaptive T cells in influenza disease

Simone Nüssing, Sneha Sant, Marios Koutsakos, Kanta Subbarao, Thi H.O. Nguyen, Katherine Kedzierska

Frontiers of Medicine 2018, Volume 12, Issue 1, Pages 34-47 doi: 10.1007/s11684-017-0606-8

Abstract: summarize the current knowledge on influenza-specific innate MAIT and gd T cells as well as adaptive CD8+sup> and CD4+sup> T cells, and discuss how these responses can be harnessed by novel vaccine

Keywords： influenza innate T cells CD4+sup> and CD8+sup> T cells vaccination

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NETO2 promotes melanoma progression via activation of the Ca/CaMKII signaling pathway

Frontiers of Medicine 2023, Volume 17, Issue 2, Pages 263-274 doi: 10.1007/s11684-022-0935-0

Abstract: proliferation, malignant growth, migration, and invasion by downregulating the levels of calcium ions (Ca2+sup>) and the expression of key genes involved in the calcium signaling pathway.

Keywords： melanoma neuropilin and tolloid-like 2 Ca2+sup>/CaMKII signaling pathway

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New Monitoring Technologies for Overhead Contact Line at 400 km·h−1sup>

Chul Jin Cho, Young Park

Engineering 2016, Volume 2, Issue 3, Pages 360-365 doi: 10.1016/J.ENG.2016.03.016

Abstract: recently been developed for high-speed railways, in order to boost commercial speeds from 300 km·h−1sup>to 400 km·h−1sup>.Among these technologies, this paper introduces the 400 km·h−1sup> class currentbeen adopted to inspect the stability of overhead contact line (OCL) components at 400 km·h−1sup> without direct contact with any components of the power supply system.

Keywords： High-speed railway Overhead contact lines Condition monitoring Image processing based measurement

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Title Author Date Type Operation

RNA m6sup>A modification and its function in diseases

Jiyu Tong, Richard A. Flavell, Hua-Bing Li

Journal Article

High frequency of alternative splicing variants of the oncogene in neuroendocrine tumors of the pancreas and breast

Journal Article

Study on Algorithm A*sup> Based on Dynamic Representation of Binary Tree for Environment and Robotic

Tang Ping,Yang Yimin

Journal Article

Clinical significance of CD34+sup>CD117dimsup>/CD34+sup>CD117brisup> myeloblast-associated

Xueping Li, Yuting Dai, Bing Chen, Jinyan Huang, Saijuan Chen, Lu Jiang

Journal Article

K+sup> and Na+sup> fluxes in roots of two Chinese Iris populations

Pinfang LI,Biao ZHANG

Journal Article

Recent Advances in 19sup>Fluorine Magnetic Resonance Imaging with Perfluorocarbon Emulsions

Wickline,Gregory M. Lanza

Journal Article

Removal of ammonium and nitrate through Anammox and FeS-driven autotrophic denitrification

Journal Article

Selective recovery of Cu

Haiping LUO,Bangyu QIN,Guangli LIU,Renduo ZHANG,Yabo TANG,Yanping HOU

Journal Article

Advances of 12thsup> CAPS research symposium: young chemists and chemical engineers fronts

Guoping Hu, Baiqian Dai

Journal Article

Effect of noble metal nanoparticle size on C–N bond cleavage performance in hydrodenitrogenation: a study of active sites

Journal Article

Symbiotic performance, shoot biomass and water-use efficiency of three groundnut (

Sofiya K. MUHABA, Felix D. DAKORA

Journal Article

Effects of La, Ce on nitrogen removal in sequencing batch reactor

Qing XIA , Rui LIANG , Yuning HONG , Lili DING , Hongqiang REN , Yuxiang MAO , Mingyu ZHAO ,

Journal Article

Innate and adaptive T cells in influenza disease

Simone Nüssing, Sneha Sant, Marios Koutsakos, Kanta Subbarao, Thi H.O. Nguyen, Katherine Kedzierska

Journal Article

NETO2 promotes melanoma progression via activation of the Ca/CaMKII signaling pathway

Journal Article

New Monitoring Technologies for Overhead Contact Line at 400 km·h−1sup>

Chul Jin Cho, Young Park

Journal Article

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